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c/glp1women·submitted 5 months ago by u/step_therapy_s

tried insulin resistance for 13 weeks. here is what happened.

Questionbranch of 10 comments

tried insulin resistance for 13 weeks. here is what happened, which sounds obvious until you try to state the evidence for it. Since the title puts numbers in the shop window: 13 weeks. Fertility changed faster than I expected with the weight loss. Nobody had raised it and I wish somebody had. The same dose genuinely…

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10 comments, started 5 months ago
u/katrin_diallo29 points·5 months ago

say what you are actually asking, the vocabulary here is imprecise

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[deleted]11 points·5 months ago

[deleted]

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u/careful_gradient4 points·5 months ago

the research gap is real and it is not your imagination

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u/blunt_coldbox_notes1 point·5 months ago

the same dose can feel different at different points in the month

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u/dilara_szabo24 points·5 months ago

symptom patterns can track the cycle rather than the dose

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u/step_therapy_sOP19 points·5 months ago

Went looking for trial data on the specific question asked here and found the population had not been enrolled.

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u/dilara_szabo15 points·5 months ago

ask a clinician about anything involving pregnancy, without exception

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u/ferran_laurent11 points·5 months ago

Small fix — insulin resistance is a feature commonly seen in PCOS, not a synonym for it.

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u/kian_solberg3 points·5 months ago

Perimenopause and all of this at once, and there is essentially nothing written about the combination anywhere.

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u/honest_syringe_20252 points·5 months ago

Perimenopause and all of this at once, and there is essentially nothing written about the combination anywhere.

This is the practical fix for half the confusing weeks on this board — annotate the cycle.

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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