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c/glp1women·posted 5 months ago by u/joaquin_trevino

[Results] 35 weeks on 2.4mg, full numbers, ask me anything boring

Results

Here it is: 35 weeks on 2.4mg, full numbers, ask me anything boring. One person, one log, no control group, so read it accordingly.

Hard numbers: 35 weeks and 2.4mg. Anything softer than that is flagged as an impression.

Trial populations for the major programmes were not designed around the questions this board asks most often, which is why the evidence base here is genuinely thinner rather than merely harder to find.

Telogen shedding follows a period of significant weight change rather than a specific compound, and it resolves.

If two or three other people have done the same thing we might actually learn something. Alone it is an anecdote.

214 up / 5 down98% upvoted20 commentsid 3afm3m17 Feb 2026

20 comments

14 in this archive, depth 5

best — the order this archive was captured in

u/low_appetite_lisa15 points·5 months ago·edited

Insulin resistance is a common feature in PCOS, which is why the metabolic conversation overlaps so heavily with this board. A diagnosis and a finding are still different things and the distinction matters for what the evidence says.

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u/valeria_cardoso18 points·5 months ago

Perimenopausal, or is that a separate question?

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u/joaquin_trevino5 points·5 months ago

Yes. The research gap is genuine; most of the trials were not designed to answer these questions.

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u/ewan_tulloch4 points·5 months ago

ask a clinician about anything involving pregnancy, without exception

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u/nnt_nate1 point·5 months ago

ask a clinician about anything involving pregnancy, without exception

This is the practical fix for half the confusing weeks on this board — annotate the cycle.

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u/ewan_zielinski2 points·5 months ago

ask a clinician about anything involving pregnancy, without exception

Disagreeing with this line: the absorption question has a product-specific answer and a pharmacist has it.

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u/joaquin_trevinoOP7 points·5 months ago

the research gap is real and it is not your imagination

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u/lipid_panel_larrybloodwork8 points·5 months ago

Hormonal variation across the cycle affects appetite, fluid retention and subjective symptom intensity independently of anything else, which is why an unannotated log can look mysterious.

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u/signe_villalobos2 points·5 months ago·edited

Are you asking about the compound, the weight loss, or both?

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u/bastian_aalto3 points·5 months ago

That is a general statement about gastric emptying, and the question was about a specific product.

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u/wholesome_lurkerMOD6 points·5 months ago

Pointing the contraception question at a pharmacist. They can answer it properly and we cannot.

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u/joaquin_trevinoOP3 points·5 months ago

log the cycle alongside the dose if you want the pattern to be visible

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u/blunt_coldbox_20241 point·5 months ago

Fertility can change with weight loss and improved insulin sensitivity. That is a well-described phenomenon and worth knowing about in advance rather than discovering.

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[removed]1 point·5 months ago

[removed by moderator]

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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