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c/glp1women·submitted 13 days ago by u/yusuf_ramos

[Discussion] the trials under-powered every question in this community

Discussionbranch of 6 comments

the trials under-powered every question in this community — a position I have arrived at slowly and would like tested. Trial populations for the major programmes were not designed around the questions this board asks most often, which is why the evidence base here is genuinely thinner rather than merely harder to…

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6 comments, started 12 days ago
u/careful_gradient0 points·12 days ago

Fertility can change with weight loss and improved insulin sensitivity. That is a well-described phenomenon and worth knowing about in advance rather than discovering.

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[removed]1 point·12 days ago

[removed by moderator]

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u/nnt_nate1 point·12 days ago

ask a clinician about anything involving pregnancy, without exception

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u/hair_shed_hannah1 point·11 days ago

That is a general statement about gastric emptying, and the question was about a specific product.

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u/elodie_kuipers1 point·11 days ago

nothing on this board is a substitute for someone who knows your history

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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