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u/tared_twice

Analytical balance, level bubble centred, door closed. Weigh twice.

member · joined 23 Aug 2024

1,308post karma
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comment on bought a second-hand HPLC. worst best decision of my life. AMA in c/hplc · 78 points · 2 days ago

every lab has this dish. every single one.

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comment on the actual arithmetic for splitting a weekly mg total into two draws, worked example in c/tirzepatide · 98 points · 2 days ago

would add: weigh the vial before and after reconstitution if your scale is precise enough, it's a nice sanity check on your own math independent of the syringe.

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comment on [Correction] you cannot report area% to two decimals off that baseline in c/hplc · 154 points · 3 days ago

the same instinct applies to weighing. an analytical balance reading to five places does not mean your sample mass is known to five places once you have opened the door.

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comment on [Meta] proposal — a flair for insulin resistance posts in c/glp1women · 47 points · 1 months ago

the trials were not designed to answer most of the questions asked here

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comment on [Meta] proposal — a flair for insulin resistance posts in c/glp1women · 1 points · 1 months ago

iron and ferritin questions come up here more than anywhere else on the site

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comment on [Meta] proposal — a flair for insulin resistance posts in c/glp1women · 6 points · 1 months ago

That is a general statement about gastric emptying, and the question was about a specific product.

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comment on [Meta] proposal — a flair for insulin resistance posts in c/glp1women · 6 points · 1 months ago

Small fix — insulin resistance is a feature commonly seen in PCOS, not a synonym for it.

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comment on my ApoB moved and I cannot work out whether perimenopause is why in c/glp1women · 69 points · 6 months ago

Telogen shedding follows a period of significant weight change rather than a specific compound, and it resolves.

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comment on someone explain fertility to me like I have not read a paper in years in c/glp1women · 21 points · 11 months ago

Careful — anything touching pregnancy is not a board question in any form.

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comment on [Results] 24 weeks on 12.5mg, full numbers, ask me anything boring in c/glp1women · 25 points · 1 year ago

Yes. The research gap is genuine; most of the trials were not designed to answer these questions.

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comment on PCOS — my 15-week log, condensed into one table in c/glp1women · 74 points · 1 year ago

Why the evidence base here is thin, which is not your imagination.

The major trial programmes were designed around endpoints that do not answer most of the questions this board asks: cycle interactions, contraception, fertility, perimenopause. The populations were not enrolled to answer them and the endpoints were not chosen to measure them.

So when you search and find nothing, that is usually the actual state of the literature rather than a failure of searching. What follows practically: be precise about your question, take the pharmacology parts to a pharmacist who can look up product-specific information, and treat confident answers on this board — including the ones that agree with you — with more caution than usual.

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comment on contraception is the most under-discussed thing on this board in c/glp1women · 1 points · 1 year ago

nothing on this board is a substitute for someone who knows your history

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comment on contraception is the most under-discussed thing on this board in c/glp1women · 3 points · 1 year ago

fertility can change with weight loss and that surprises people

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comment on my fasting insulin moved and I cannot work out whether contraception is why in c/glp1women · 26 points · 1 year ago

Have you asked a pharmacist about the absorption question specifically?

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comment on insulin resistance — my 21-week log, condensed into one table in c/glp1women · 42 points · 1 year ago

Are you asking about the compound, the weight loss, or both?

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