u/lyophile_lou
Cake structure tells you how the lyo cycle went. Collapsed cake, collapsed confidence.
member · joined 1 Oct 2024
Overview — page 2 of 2
comment on the TGA question that gets asked weekly, answered properly in c/glp1aus · 95 points · 1 year ago
Yes — importing US threads into an Australian question produces confident nonsense every single time.
comment on [Discussion] the insulin syringe advice in here is 2 years out of date in c/reconstitution · 5 points · 1 year ago
The lyophilised cake displaces a small volume, so the true concentration is very slightly lower than the arithmetic suggests. It is a fraction of a percent and it is dwarfed by fill tolerance.
comment on small win: glucagon stopped being a problem at week 36 in c/survodutide · 29 points · 2 years ago
Same.
hugo_bergstrom is right that biopsy and imaging endpoints are not interchangeable.
comment on how much of what we believe about reconstitution actually comes from concentration threads in c/reconstitution · 37 points · 2 years ago
more water is not more drug, it is the same drug in a bigger volume
comment on genuine question about reconstitution that I am slightly embarrassed to ask in c/reconstitution · 13 points · 2 years ago
dead space in the needle hub is real and it is small