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u/liver_enzyme_liz

ALT dropped 34 to 19. The fatty-liver story is the underrated one.

member · joined 14 Apr 2024

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Overview — page 2 of 3

comment on stalled for 2 weeks at 15mg and I refuse to panic this time in c/newbiequestions · 34 points · 4 months ago

A certificate of analysis is a document describing one batch: what was tested, by what method, and what the result was. Its value depends entirely on whether it names the batch and the method.

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comment on week one is the most under-discussed thing on this board in c/newbiequestions · 1 points · 4 months ago

A certificate of analysis is a document describing one batch: what was tested, by what method, and what the result was. Its value depends entirely on whether it names the batch and the method.

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comment on small win: ALT stopped being a problem at week 87 in c/bloodwork · 4 points · 4 months ago

the trend line matters more than any single value

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comment on small win: ALT stopped being a problem at week 87 in c/bloodwork · 51 points · 4 months ago

Identifying header cropped from the report above. Post the values, not the name and reference number.

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comment on small win: ALT stopped being a problem at week 87 in c/bloodwork · 78 points · 4 months ago

Did anything else change in that window — training, intake, hydration?

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comment on anyone else notice what is kicking in around week 86 in c/newbiequestions · 63 points · 4 months ago

The five things that would have saved me the most time in month one.

One: the first month is a tolerance check, not a results phase. Two: appetite usually changes before the scale does, so watch that instead. Three: write the concentration and the date on the vial the moment you reconstitute anything. Four: the loud posts are not the middle of the distribution. Five: nobody here — including whoever answers most confidently — is your clinician.

None of that is advice about what to take. It is the shape of the first few weeks, which is what I actually wanted and could not find.

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comment on genuine question about API source that I am slightly embarrassed to ask in c/compounding · 23 points · 4 months ago

Agreed. The 503A versus 503B distinction changes who is allowed to make what, and almost every confused thread here starts by ignoring it.

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comment on how much of what we believe about eGFR actually comes from ferritin threads in c/bloodwork · 117 points · 5 months ago

Standing reminder: nobody here interprets your results, and posts asking us to get a pointer to somebody who can.

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comment on [Results] 88 weeks on 2.4mg, full numbers, ask me anything boring in c/retatrutide · 1.1k points · 5 months ago

Glucagon receptor agonism is associated with increased energy expenditure and with hepatic effects. That is a mechanistic story with strong preclinical support and limited phase 2 human data.

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comment on genuine question about shortage list that I am slightly embarrassed to ask in c/compounding · 16 points · 5 months ago

Careful. Naming a clinic without describing what actually happened turns this into a different kind of thread.

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comment on help me understand triple agonist, I have read the wiki twice in c/retatrutide · 48 points · 5 months ago

How fast was the escalation? That is usually the variable that explains the reports.

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comment on MASH — my 24-week log, condensed into one table in c/survodutide · 34 points · 5 months ago

Removed the escalation schedule. Unapproved compound, no protocols for other members, no exceptions.

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comment on my TSH moved and I cannot work out whether ferritin is why in c/bloodwork · 17 points · 6 months ago

Left up. It is a question about how to compare panels, not a request for interpretation.

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comment on stalled for 3 weeks at 1.7mg and I refuse to panic this time in c/bloodwork · 32 points · 6 months ago

Fasting or not, and what time of day?

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comment on stalled for 3 weeks at 1.7mg and I refuse to panic this time in c/bloodwork · 73 points · 6 months ago

Nobody here can interpret your panel and this comment is not doing so. What a board can usefully do is help you ask better questions of somebody who can.

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comment on week 71 check-in — 23kg down, muscle cramps manageable, one thing confusing me in c/bloodwork · 39 points · 6 months ago

Careful — that is a question for whoever ordered the panel, and nobody in this thread can answer it responsibly.

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comment on help me understand glucagon, I have read the wiki twice in c/retatrutide · 89 points · 7 months ago

Has anyone posted an independent test on this compound recently?

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comment on genuine question about ApoB that I am slightly embarrassed to ask in c/bloodwork · 13 points · 7 months ago

ApoB is the one worth adding if you only add one

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comment on dual agonist — 21 things I got wrong before I got it right in c/survodutide · 39 points · 7 months ago

Independent result logged. There are almost none for this compound, so it is genuinely valuable.

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comment on week 31 check-in — 11kg down, sulphur burps manageable, one thing confusing me in c/bloodwork · 5 points · 7 months ago

fasting state and time of day change more than people expect

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comment on someone explain first time to me like I have not read a paper in years in c/newbiequestions · 30 points · 7 months ago

Which country? Half the answers here only apply in one place.

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comment on [Discussion] ApoB is doing more work than we give it credit for in c/bloodwork · 1 points · 8 months ago

Agreed on assay changes. A lab switching platforms between your draws is invisible unless you ask.

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comment on week 36 check-in — 12kg down, nausea manageable, one thing confusing me in c/survodutide · 5 points · 8 months ago

Left up. It reads the paper carefully and is explicit about the population.

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comment on what would you tell week-1 you about lipids in c/bloodwork · 1 points · 8 months ago

Compared two draws across two labs and spent a week worrying before finding out the assays were different.

Adding the obvious one — take it to whoever ordered the panel. This board cannot read it for you.

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comment on three years of bloodwork threads, summarised so you do not have to read them in c/bloodwork · 5 points · 9 months ago

do not change three things and then read the panel

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comment on [Question] TRIUMPH — what am I missing here in c/retatrutide · 162 points · 9 months ago

Small fix — three receptors, not two. GLP-1, GIP and glucagon, and the third one is the reason this compound gets its own board.

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comment on the telehealth question that gets asked weekly, answered properly in c/compounding · 5 points · 9 months ago

shortage status changes and the whole arrangement changes with it

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comment on [Meta] proposal — a flair for baseline labs posts in c/bloodwork · 1 points · 9 months ago

Retitled — the original asserted a causal claim the post does not support.

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comment on small win: hepatic fat stopped being a problem at week 91 in c/survodutide · 16 points · 9 months ago

Independent result logged. There are almost none for this compound, so it is genuinely valuable.

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comment on my ALT moved and I cannot work out whether beginner is why in c/newbiequestions · 22 points · 10 months ago

Small correction, said kindly: those are two different products with similar names, and the difference matters for a multi-draw vial.

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comment on my ALT moved and I cannot work out whether beginner is why in c/newbiequestions · 58 points · 10 months ago

A certificate of analysis is a document describing one batch: what was tested, by what method, and what the result was. Its value depends entirely on whether it names the batch and the method.

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comment on [Discussion] MASH is doing more work than we give it credit for in c/survodutide · 1 points · 11 months ago

That is an escalation schedule for an unapproved compound and this board does not host those.

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comment on [Results] 24 weeks on 2.5mg, full numbers, ask me anything boring in c/newbiequestions · 1 points · 11 months ago

ask the dumb question, three other people are searching for it

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comment on the bloodwork question that gets asked weekly, answered properly in c/bloodwork · 12 points · 1 year ago

Standing reminder: nobody here interprets your results, and posts asking us to get a pointer to somebody who can.

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comment on the TRIUMPH thing finally clicked for me and I want to write it down in c/retatrutide · 0 points · 1 year ago

The phase 2 readout ran to 48 weeks in a few hundred participants with a slow escalation. Both the size and the duration matter when people quote the headline number.

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comment on the biopsy question that gets asked weekly, answered properly in c/survodutide · 5 points · 1 year ago

Retitled to name the endpoint. Histological and imaging results are not interchangeable and the original title implied they were.

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comment on small win: basics stopped being a problem at week 85 in c/newbiequestions · 42 points · 1 year ago

The vocabulary, once, since half the questions here are really vocabulary questions.

Titration is stepping the dose up slowly for tolerance. Reconstitution is adding water to a freeze-dried powder. Bacteriostatic water contains a preservative; sterile water does not. COA is a certificate of analysis — a lab document about one batch. Area percent is a purity measure from that document, and it is not the amount of peptide in the vial. Units are a volume on an insulin syringe, not a dose.

That is most of the jargon on this site. The wiki has the longer version of each and it is linked in the sidebar.

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comment on three years of MASH threads, summarised so you do not have to read them in c/survodutide · 20 points · 1 year ago

Left up. It reads the paper carefully and is explicit about the population.

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comment on three years of MASH threads, summarised so you do not have to read them in c/survodutide · 2 points · 1 year ago

Independent purity results for this compound are very sparse across the whole site, which means any impression about consistency is built on almost nothing.

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