u/liv_nkemelu
Contributes reviews on supplier material. Based in Kaunas.
member · joined 12 Mar 2025
comment on [TGA] shortage notice archive, worth bookmarking in c/glp1aus · 12 points · 9 days ago
Small fix — that is the New Zealand arrangement, and the question is about Australia.
comment on water content is on the COA and everyone skips it in c/coa · 29 points · 10 days ago
Related substances itemised individually is a much stronger document than a single total, because it tells you the shape of the impurity profile rather than its size.
comment on Denmark: compounding, and what it actually costs here in c/glp1aus · 7 points · 14 days ago
personal importation rules exist and are narrow
comment on Denmark: compounding, and what it actually costs here in c/glp1aus · 5 points · 15 days ago
PBS criteria are published and searchable
comment on Denmark: compounding, and what it actually costs here in c/glp1aus · 17 points · 15 days ago
What did the pharmacy quote for the private price?
comment on how do i tell an HPLC-UV COA from an LC-MS one at a glance in c/coa · 1 points · 25 days ago
chromatogram or it did not happen
comment on [PeptideMeter] ERP tirz 15mg — 98.4% and a very clean trace in c/labresults · 7 points · 1 months ago
Yes — date of analysis, because a result from two years ago describes a different manufacturing month.
comment on [Lab] 6th independent test on HJ — 99.1% on a claimed 99.0%, and the trend is the interesting part in c/coa · -25 points · 1 months ago
My first certificate had a compound name, a percentage and a logo. I thought that was normal. It is not, and now I know what to ask for.
comment on three years of reconstitution threads, summarised so you do not have to read them in c/reconstitution · 20 points · 1 months ago
Corrected the concentration in the title, which contradicted the body.
vial_math_vera has the units point exactly right. They are a volume on the barrel and nothing else.
comment on someone explain concentration to me like I have not read a paper in years in c/reconstitution · 220 points · 1 months ago
Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person.
comment on [Below Spec] 94.1% with a 1.8% single impurity. is that the des-amido in c/labresults · 1 points · 1 months ago
area percent unless the report says otherwise
clara_weiss is right that the band matters more than the peak. Consistency across lots is the finding.
comment on [Meta] proposal — a flair for compounding posts in c/glp1aus · 28 points · 1 months ago
The compounded arrangements changed while I was mid-thread and I was arguing from a superseded position.
comment on the area percent question that gets asked weekly, answered properly in c/coa · 1 points · 1 months ago
Correction: that is net peptide content, not purity. Different number, different meaning, and the document says so if you read the row label.
comment on [Below Spec] 94.1% with a 1.8% single impurity. is that the des-amido in c/labresults · 1 points · 1 months ago
The template is vendor, compound, batch, service, claim, result, and who paid. Every one of those fields exists because a result missing it has been argued about here before.
comment on [Janoshik] FGP cagrilintide — first independent number i have seen for it in c/labresults · 34 points · 1 months ago
SGN came back 98.0% on a claimed 97.5%, which is agreement not a discrepancy
comment on [Janoshik] FGP cagrilintide — first independent number i have seen for it in c/labresults · 53 points · 1 months ago
one result is a data point, agreement between two services is evidence
comment on [Meta] proposal — a flair for PeptideMeter posts in c/labresults · 31 points · 1 months ago
Is that the same lot as the one in the thread from last month?
comment on how much of what we believe about area percent actually comes from COA threads in c/coa · 228 points · 1 months ago
net peptide content and purity are two different numbers on the same vial
comment on genuine question about area percent that I am slightly embarrassed to ask in c/coa · 342 points · 2 months ago
a total of 0.4% tells you less than four named impurities adding to 0.6%
comment on help me understand COA, I have read the wiki twice in c/coa · 11 points · 2 months ago
Asked BCH for the batch-specific certificate and had the full document — batch, date, method line naming the column — inside six hours. That is now my baseline for everybody.
comment on why does nobody talk about area percent in c/coa · 1 points · 2 months ago
Did you ask for the batch-specific document, or is this the catalogue one?
comment on how much of what we believe about mg/mL actually comes from insulin syringe threads in c/reconstitution · 28 points · 2 months ago
Disagree with the "more water is safer" framing. It is not safer, it is just a different number to divide by.
comment on genuine question about concentration that I am slightly embarrassed to ask in c/reconstitution · 97 points · 3 months ago
Research-use-only material is not approved for human use, so treat everything in this thread as arithmetic about solutions rather than instructions for a person.
comment on [Question] how do you actually verify Janoshik in c/labresults · 1 points · 3 months ago
split a vial across two services once and you will never argue about ground truth again
comment on related substances are the most under-discussed thing on this board in c/coa · 11 points · 5 months ago
Same view. QYB prints the column and the gradient, which means somebody could actually reproduce the run.
comment on three years of concentration threads, summarised so you do not have to read them in c/reconstitution · 26 points · 6 months ago
If your calculation produces a fraction of a unit, the concentration is wrong for your dose.
Right, and the arithmetic behind it: 15mg in 3mL is 5mg/mL, so 0.5mg is 10 units.
comment on reading water content threads from 2024 and half of it aged badly in c/coa · 37 points · 6 months ago
Ask what the stability statement was written against — temperature, light, and whether it was the lyophilised powder or the reconstituted solution. Those are three different claims.
comment on [Discussion] we are measuring PBS at the wrong time and calling it noise in c/glp1aus · 6 points · 6 months ago
Cosigning on asking the pharmacy to check the wholesaler. It converts speculation into a fact in one phone call.
comment on unpopular opinion: most of what gets said here about test results are guesswork in c/labresults · 18 points · 6 months ago
three lots beats three tests on one lot
comment on the units thing finally clicked for me and I want to write it down in c/reconstitution · 25 points · 6 months ago
label the vial with the date as well as the concentration
comment on three years of related substances threads, summarised so you do not have to read them in c/coa · 108 points · 7 months ago
Right, and net peptide content is where the counterion and the water go. Both numbers can be honest and very different.
comment on help me understand shortage, I have read the wiki twice in c/glp1aus · 32 points · 7 months ago
PBS criteria are published and searchable
comment on mg/mL is the most under-discussed thing on this board in c/reconstitution · 22 points · 10 months ago
do the arithmetic before you reconstitute, not while holding a syringe
comment on [Question] how do you actually verify units in c/reconstitution · 370 points · 10 months ago
Agreed — units are volume. Once that lands, the rest of the arithmetic is one division.
comment on [PSA] Janoshik is not what most of this community thinks it is in c/labresults · 1 points · 10 months ago
net peptide content if the report gives it, and say which you are quoting
comment on purity — 9 things I got wrong before I got it right in c/coa · 0 points · 1 year ago
Related substances itemised individually is a much stronger document than a single total, because it tells you the shape of the impurity profile rather than its size.
comment on [Lab] 18th independent test on GL Biochem — 99.5% on a claimed 99.0%, and the trend is the interesting part in c/labresults · 71 points · 1 year ago
say whether you paid for it yourself
comment on someone explain PeptideMeter to me like I have not read a paper in years in c/labresults · 54 points · 1 year ago
Area percent or net peptide content?
comment on how much of what we believe about purity actually comes from related substances threads in c/coa · 1 points · 1 year ago
Not quite. Two labs with different gradients can resolve a close-eluting impurity differently and both be reporting honestly.
comment on [Question] is 99.0% actually fine or am I being sold a rounding error in c/coa · 181 points · 1 year ago
Cosigning. The batch identifier is load-bearing, and a certificate that cannot be tied to the vial in your hand is not about your vial.