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KA

u/karl_fischer_kev

Residual moisture matters more than you think. Water content is a purity story.

member · joined 8 Jun 2024

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103comments

Overview — page 3 of 3

comment on the ApoB thing finally clicked for me and I want to write it down in c/bloodwork · 392 points · 1 year ago

Not convinced by the attribution. Weight loss alone moves that marker and you have no way to separate the two.

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comment on [Question] mg/mL — what am I missing here in c/reconstitution · 124 points · 1 year ago

dead space in the needle hub is real and it is small

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comment on [Discussion] the insulin syringe advice in here is 2 years out of date in c/reconstitution · 3 points · 1 year ago

Disagree with the "more water is safer" framing. It is not safer, it is just a different number to divide by.

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comment on [Discussion] can we stop arguing about eGFR until somebody posts a number in c/bloodwork · 16 points · 1 year ago

ask whether the lab changed its assay between your two draws

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comment on [Discussion] can we stop arguing about eGFR until somebody posts a number in c/bloodwork · -21 points · 1 year ago

Careful — that is a question for whoever ordered the panel, and nobody in this thread can answer it responsibly.

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comment on reading eGFR threads from 2024 and half of it aged badly in c/bloodwork · 17 points · 1 year ago

Agreed on assay changes.

Adding the obvious one — take it to whoever ordered the panel. This board cannot read it for you.

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comment on small win: perimenopause stopped being a problem at week 52 in c/glp1women · 74 points · 2 years ago

symptom patterns can track the cycle rather than the dose

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comment on help me understand SURMOUNT, I have read the wiki twice in c/trialwatch · 36 points · 2 years ago

Why comparing across trials almost never works, with the specific failure modes.

Adding the check nobody runs — the registered protocol is public and takes two minutes to compare.

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comment on [Results] 47 weeks on 0.5mg, full numbers, ask me anything boring in c/glp1muscle · 35 points · 2 years ago

Protein was the whole problem. Appetite dropped and I was eating well under target without noticing for a month.

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comment on SURPASS — 12 things I got wrong before I got it right in c/trialwatch · 152 points · 2 years ago

This. Intention-to-treat versus completer analysis routinely moves the headline by several points.

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comment on why does nobody talk about waist in c/dosinglogs · 22 points · 2 years ago

I would not draw a trend line through that. Two points and a gap is not a series.

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comment on nobody warned me about reflux and I would have liked the warning in c/bloodwork · 35 points · 2 years ago

Do you have a baseline from before you started?

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comment on [Discussion] the crypto advice in here is 2 years out of date in c/cryptopay · 142 points · 2 years ago

Sent a test amount first on a large order. Cost me a fraction of a percent and I have done it every time since.

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comment on baseline labs are the most under-discussed thing on this board in c/bloodwork · 248 points · 2 years ago

Different laboratories use different assay platforms with different calibration. Comparing across labs adds a systematic offset that is invisible on the report.

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comment on [Discussion] the endpoint advice in here is 3 years out of date in c/trialwatch · 358 points · 2 years ago

intention to treat versus completers changes the number substantially

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comment on [Discussion] can we stop arguing about ApoB until somebody posts a number in c/bloodwork · 0 points · 2 years ago

Did anything else change in that window — training, intake, hydration?

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comment on [Discussion] can we stop arguing about ApoB until somebody posts a number in c/bloodwork · 40 points · 2 years ago

lab reference ranges are not treatment targets

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comment on [Discussion] can we stop arguing about ApoB until somebody posts a number in c/bloodwork · -26 points · 2 years ago

What did the repeat show?

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comment on the baseline labs question that gets asked weekly, answered properly in c/bloodwork · 103 points · 2 years ago

a single ApoB outside range is a reason to repeat, not to panic

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comment on the baseline labs question that gets asked weekly, answered properly in c/bloodwork · 302 points · 2 years ago

Nobody here can interpret your panel and this comment is not doing so. What a board can usefully do is help you ask better questions of somebody who can.

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comment on [Discussion] we are measuring mg/mL at the wrong time and calling it noise in c/reconstitution · 203 points · 2 years ago

Agreed on the swirl. There is no reason to shake it and a good reason not to.

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comment on how much of what we believe about reconstitution actually comes from concentration threads in c/reconstitution · 158 points · 2 years ago

I would not round that figure. At 5mg/mL a rounding error of two units is a real fraction of the intended amount.

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comment on [Results] 78 weeks on 12.5mg, full numbers, ask me anything boring in c/bloodwork · 1 points · 2 years ago

ask whether the lab changed its assay between your two draws

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comment on [Question] how do you actually verify insulin syringe in c/reconstitution · 216 points · 2 years ago

Is that a U-100 syringe? The barrel markings change the answer completely.

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comment on bacteriostatic water — 16 things I got wrong before I got it right in c/reconstitution · 0 points · 2 years ago

Agreed — units are volume. Once that lands, the rest of the arithmetic is one division.

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