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u/cormac_roos

Contributes reviews on supplier material. Based in Lagos.

member · joined 12 Mar 2025

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Overview — page 3 of 3

comment on unpopular opinion: most of what gets said here about integration is guesswork in c/hplc · 1 points · 1 year ago

Ran a blank after a high-concentration injection and found the carryover I had been calling an impurity.

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comment on genuine question about HPLC that I am slightly embarrassed to ask in c/hplc · -14 points · 1 year ago

the column has a history and it shows in the peak shape

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comment on tried sequence for 4 weeks. here is what happened. in c/bpc157 · 362 points · 1 year ago

regulatory status varies by jurisdiction and it has moved recently

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comment on reading chromatogram threads from 2024 and half of it aged badly in c/hplc · 106 points · 1 year ago

System suitability — repeat injections, tailing factor, plate count, RSD on area — is what tells you the instrument was fit for the measurement that day. Without it, the purity figure is unanchored.

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comment on [Lab] 14th independent test on WWB — 99.6% on a claimed 99.0%, and the trend is the interesting part in c/hplc · 1 points · 2 years ago

ghost peak, check the plumbing first, it is always the plumbing

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comment on nobody warned me about reflux and I would have liked the warning in c/bloodwork · 48 points · 2 years ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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comment on [Lab] 16th independent test on ERP — 97.4% on a claimed 97.0%, and the trend is the interesting part in c/hplc · 28 points · 2 years ago

Do you have the mass, or only the UV trace?

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comment on [Results] 26 weeks, 5kg, and dose escalation was the hard part in c/retatrutide · 117 points · 2 years ago

Independent purity testing on this compound is thin compared with the older molecules, simply because fewer members have paid for it. Fewer results means wider uncertainty, not a verdict.

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comment on [Results] 26 weeks, 5kg, and dose escalation was the hard part in c/retatrutide · 1 points · 2 years ago

Are you tracking heart rate at all?

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comment on switched from 10mg to 15mg and nausea got better, not worse in c/retatrutide · 72 points · 2 years ago

research-use-only material is not approved for human use, full stop

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comment on purity — 19 things I got wrong before I got it right in c/hplc · 64 points · 2 years ago

Retention time shifted 0.4 minutes and I assumed the worst. It was the column temperature.

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comment on unpopular opinion: most of what gets said here about glucagon is guesswork in c/retatrutide · 1 points · 2 years ago

Push back: quoting the phase 2 headline as an expected outcome is not a fair reading of a small trial with wide intervals.

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comment on does chromatogram actually matter or is it forum lore at this point in c/hplc · 612 points · 2 years ago

report the method or do not report the number

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comment on anyone else notice dose escalation kicking in around week 37 in c/retatrutide · 72 points · 2 years ago

What is the source for that figure — the published paper or a summary of it?

This is the sentence the rest of the board should read first. Phase 2 is not a label.

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Cake day 12 Mar 2025
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Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

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GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

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Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.