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u/anecdata_annie

One person is not a study. One hundred people is not a study either.

member · joined 25 Aug 2024

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Comments — page 2 of 2

comment on [PSA] area percent is not what most of this community thinks it is in c/coa · 1 points · 1 year ago

Pushing back a little: a missing field is usually presentation, not concealment. Ask for the full document before drawing conclusions.

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comment on the batch question that gets asked weekly, answered properly in c/coa · 2 points · 1 year ago

Cosigning. The batch identifier is load-bearing, and a certificate that cannot be tied to the vial in your hand is not about your vial.

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comment on [Discussion] New Zealand is doing more work than we give it credit for in c/glp1aus · 43 points · 1 year ago

the price you pay depends on the listing status of your indication

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comment on the TGA thing finally clicked for me and I want to write it down in c/glp1aus · 17 points · 1 year ago

Pharmacy-level availability and national supply are different questions: a pharmacy can be out while the wholesaler is not, and the pharmacist can check in minutes.

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comment on why does nobody talk about water content in c/coa · 256 points · 1 year ago

Asked WXT for the batch-specific certificate and had the full document — batch, date, method line naming the column — inside six hours. That is now my baseline for everybody.

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comment on [Meta] the Australia rule is doing its job and people should stop complaining in c/glp1aus · 11 points · 1 year ago

the shortage listing has an expected resolution date on it

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comment on [Lab] split one vial across Janoshik and Medutest — 98.1% and 97.6% in c/coa · 1 points · 1 year ago

chromatogram or it did not happen

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comment on three years of water content threads, summarised so you do not have to read them in c/coa · 1 points · 1 year ago

I would not read a rounded figure as evasive. Plenty of documents round to one decimal as house style.

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comment on how much of what we believe about batch actually comes from related substances threads in c/coa · 146 points · 2 years ago

What does the method line actually say?

Disagree on this specific point. Two honest labs can resolve that impurity differently and report different numbers.

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comment on [Discussion] related substances are doing more work than we give it credit for in c/coa · 0 points · 2 years ago

Why the same vial can honestly produce three different numbers.

Purity by area percent is relative to what the detector saw on one gradient at one wavelength. Net peptide content subtracts counterion, water and residual solvent. Mass of peptide per vial is net content times fill weight, and fill weight has its own tolerance.

So a document reading 99% purity, 6% acetate and 4% water is describing a vial that is about 90% peptide by mass, and every one of those numbers is honest. The mistake is treating the headline figure as the answer to "how much peptide did I get".

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comment on reading area percent threads from 2024 and half of it aged badly in c/coa · 241 points · 2 years ago

Yes — and the reason to ask for the whole page is that the interesting parts are the ones people crop out to fit a screenshot.

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comment on [Meta] proposal — a flair for batch posts in c/coa · 47 points · 2 years ago

axis labels included, always

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comment on [Meta] proposal — a flair for batch posts in c/coa · 31 points · 2 years ago

Are the related substances itemised or is it a single total?

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comment on unpopular opinion: most of what gets said here about water content is guesswork in c/coa · -37 points · 2 years ago

net peptide content and purity are two different numbers on the same vial

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