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c/orforglipron·submitted 3 months ago by u/first_hundred

week 66 check-in — 26kg down, fatigue manageable, one thing confusing me

Speculationbranch of 9 comments

week 66 check-in — 26kg down, fatigue manageable, one thing confusing me. Full detail below, and I have tried to keep the editorialising out of it. Pulling the figures out of the title: week 66 and 26kg. All of it is written down as it happened rather than reconstructed. Compared milligram figures across two…

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9 comments, started 3 months ago
u/anders_karlsen41 points·3 months ago

Yes — nothing containing this is approved anywhere, and the threads keep forgetting it.

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u/incretin_ivypharmacology-26 points·3 months ago

a non-peptide agonist does not degrade the way a peptide does

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u/batch_number_bertievetting1 point·3 months ago·edited

a non-peptide agonist does not degrade the way a peptide does

Adding the standing caveat — unapproved, and research material is not for human use.

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[deleted]15 points·3 months ago

[deleted]

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u/batch_number_bertievetting14 points·3 months ago

small molecule, not a peptide, and that changes everything about it

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u/mateusz_mensah24 points·3 months ago·edited

Yes — nothing containing this is approved anywhere, and the threads keep forgetting it.

Agreed, and it is why the oral peptide comparison keeps misleading people.

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u/fasting_insulin_f11 points·3 months ago

Agreed, and it is why the oral peptide comparison keeps misleading people.

mateusz_mensah is right that milligram comparisons across classes tell you nothing.

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u/ahmed_okafor7 points·3 months ago·edited

mateusz_mensah is right that milligram comparisons across classes tell you nothing.

Disagreeing with this bit: daily dosing is a different adherence problem, not a better one.

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u/dilara_weiss3 points·3 months ago

Disagreeing with this bit: daily dosing is a different adherence problem, not a better one.

This is the fact the whole board hangs on. Small molecule, not peptide.

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