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c/glp1women·posted 9 months ago by u/greta_nilsen

perimenopause — my 15-week log, condensed into one table

Discussion

perimenopause — my 15-week log, condensed into one table. Making the case below, and I expect to lose some of it in the comments.

Questions about oral contraceptive absorption and gastric emptying are legitimate pharmacology questions with product-specific answers. A pharmacist can answer them properly; a board cannot.

Hormonal variation across the cycle affects appetite, fluid retention and subjective symptom intensity independently of anything else, which is why an unannotated log can look mysterious.

Insulin resistance is a common feature in PCOS, which is why the metabolic conversation overlaps so heavily with this board. A diagnosis and a finding are still different things and the distinction matters for what the evidence says.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

92 up / 4 down96% upvoted14 commentsid 7q63p78 Oct 2025

14 comments

14 in this archive, depth 6

best — the order this archive was captured in

u/blunt_coldbox_202424 points·9 months ago

Fertility can change with weight loss and improved insulin sensitivity. That is a well-described phenomenon and worth knowing about in advance rather than discovering.

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u/gentle_correctionMOD15 points·9 months ago

Pointing the contraception question at a pharmacist. They can answer it properly and we cannot.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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