fertility: what the trials say vs what this community says
fertility: what the trials say vs what this community says. I have gone back and forth on this for months.
Fertility can change with weight loss and improved insulin sensitivity. That is a well-described phenomenon and worth knowing about in advance rather than discovering.
Insulin resistance is a common feature in PCOS, which is why the metabolic conversation overlaps so heavily with this board. A diagnosis and a finding are still different things and the distinction matters for what the evidence says.
Hormonal variation across the cycle affects appetite, fluid retention and subjective symptom intensity independently of anything else, which is why an unannotated log can look mysterious.
Tell me where this is wrong. That is the useful part of posting it.
best — the order this archive was captured in
Why the evidence base here is thin, which is not your imagination.
The major trial programmes were designed around endpoints that do not answer most of the questions this board asks: cycle interactions, contraception, fertility, perimenopause. The populations were not enrolled to answer them and the endpoints were not chosen to measure them.
So when you search and find nothing, that is usually the actual state of the literature rather than a failure of searching. What follows practically: be precise about your question, take the pharmacology parts to a pharmacist who can look up product-specific information, and treat confident answers on this board — including the ones that agree with you — with more caution than usual.
Why the evidence base here is thin, which is not your imagination.
Disagreeing with this line: the absorption question has a product-specific answer and a pharmacist has it.
Questions about oral contraceptive absorption and gastric emptying are legitimate pharmacology questions with product-specific answers. A pharmacist can answer them properly; a board cannot.
Retitled to distinguish a cycle-linked pattern from a dose-linked one.
Retitled to distinguish a cycle-linked pattern from a dose-linked one.
Adding the one thing nobody warns about — fertility can change, and quickly.
Started logging the cycle in the same sheet as the dose. Three months later the pattern was obvious and it had been invisible before.
Careful — anything touching pregnancy is not a board question in any form.
The same dose genuinely feels different at different points in the month for me. Took a year to notice and it was in the log the whole time.
the same dose can feel different at different points in the month
the trials were not designed to answer most of the questions asked here
cycle timing changes how the same week feels
cycle timing changes how the same week feels
santiago_marchetti is right that a diagnosis and a finding are different things here.
perimenopause and this overlap in ways nobody has good data on
Not convinced by the attribution. That pattern tracks the cycle in your own log more closely than it tracks the dose.
- 1Careful — anything touching pregnancy is not a board question in any form.8 comments in this branch · started by u/santiago_marchetti