u/heart_rate_bump
Resting HR up 6bpm on titration, back down at maintenance. n=1, tracked daily.
member · joined 30 Apr 2024
Comments — page 3 of 3
comment on hazard ratio is the most under-discussed thing on this board in c/trialwatch · 0 points · 1 year ago
Same.
Adding the check nobody runs — the registered protocol is public and takes two minutes to compare.
comment on [Discussion] can we stop arguing about MHRA until somebody posts a number in c/glp1uk · 348 points · 1 year ago
Scotland, Wales and Northern Ireland have their own arrangements. An answer that begins with "in England" should say so, and most of the confusion here comes from answers that do not.
comment on glucagon is the most under-discussed thing on this board in c/survodutide · 160 points · 1 year ago
Which endpoint — histological response, fibrosis improvement, or fat fraction?
comment on reading SURMOUNT threads from 2024 and half of it aged badly in c/trialwatch · 371 points · 1 year ago
SELECT was cardiovascular outcomes, not weight
comment on [Discussion] we are measuring research peptides at the wrong time and calling it noise in c/researchpeptides · 16 points · 1 year ago
Identity confirmed, or purity only?
Adding the practical question — stocked or made to order, and what is the lead time.
comment on glucagon: what the trials say vs what this community says in c/retatrutide · 3 points · 1 year ago
the phase 2 numbers were striking and they were also 48 weeks in a small population
Agreed, and the glucagon arm is exactly why the comparison threads do not work.
comment on reading eGFR threads from 2024 and half of it aged badly in c/bloodwork · 21 points · 1 year ago
nothing on this board interprets your results for you
comment on stalled for 7 weeks at 10mg and I refuse to panic this time in c/retatrutide · 7 points · 2 years ago
Small fix — three receptors, not two. GLP-1, GIP and glucagon, and the third one is the reason this compound gets its own board.
comment on nobody warned me about reflux and I would have liked the warning in c/bloodwork · 1 points · 2 years ago
Same lab as the previous draw?
comment on why does nobody talk about MASH in c/survodutide · 1 points · 2 years ago
Right, and the trial titration was slow for reasons that are visible in the tolerability tables.
comment on why does nobody talk about MASH in c/survodutide · 37 points · 2 years ago
Imaging-derived liver fat fraction is a surrogate. It correlates with histology imperfectly, and a trial reporting one is not reporting the other.
comment on anyone else notice glucagon kicking in around week 47 in c/survodutide · 35 points · 2 years ago
Independent purity results for this compound are very sparse across the whole site, which means any impression about consistency is built on almost nothing.
comment on the baseline labs question that gets asked weekly, answered properly in c/bloodwork · 16 points · 2 years ago
Panicked about a single result, posted here, got told to repeat it, repeated it, and it was fine.
comment on reading SURMOUNT threads from 2024 and half of it aged badly in c/trialwatch · 190 points · 2 years ago
phase 2 finds a dose, phase 3 measures the effect
comment on unpopular opinion: most of what gets said here about hazard ratio is guesswork in c/trialwatch · 139 points · 2 years ago
FLOW was kidney outcomes and it is the one nobody quotes
comment on anyone else notice baseline labs kicking in around week 7 in c/bloodwork · 89 points · 2 years ago
Careful — that is a question for whoever ordered the panel, and nobody in this thread can answer it responsibly.
comment on [PSA] lipids are not what most of this community thinks it is in c/bloodwork · 82 points · 2 years ago
Not convinced by the attribution. Weight loss alone moves that marker and you have no way to separate the two.
comment on [Results] 45 weeks on 10mg, full numbers, ask me anything boring in c/retatrutide · 7 points · 2 years ago
small trial, big effect, wide error bars
comment on anyone else notice dose escalation kicking in around week 37 in c/retatrutide · 33 points · 2 years ago
Is that the 48-week figure or an earlier readout?
comment on anyone else notice dose escalation kicking in around week 37 in c/retatrutide · 1 points · 2 years ago
Watched heart rate on a wearable across twelve weeks because the threads said to. It moved a little and I have no idea whether that means anything.
comment on anyone else notice dose escalation kicking in around week 37 in c/retatrutide · 1 points · 2 years ago
What do you think the glucagon component is adding, specifically?